Cattle Drive Dish

Featured in Delicious Main Dish Recipes for Every Occasion.

This hearty dish packs layers of tasty spiced beef, colorful veggies, and a cheesy, creamy top. It starts with a partially baked biscuit crust, followed by seasoned ground beef, sweet corn, and tangy tomatoes. The creamy layer of sour cream, cheddar, mayo, and green chilies finishes it off. Baked until bubbly and golden, it's a cozy mealtime option that’s ready in around an hour. Perfect for casual dinners or gatherings—your family will love it!

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Updated on Tue, 20 May 2025 19:04:14 GMT
A white bowl filled with a warm casserole dish. Pin it
A white bowl filled with a warm casserole dish. | chefmelt.com

This ranch-inspired bake brings home-style comfort straight to your dinner table. The tasty combo of seasoned beef, veggies, and smooth topping makes a filling one-pot meal that's great for busy nights or when you've got lots of hungry folks to feed.

I whipped this up for the first time when feeding my hubby's starving workmates after they'd been working the ranch all day. The scraped-clean dish and folks asking how I made it told me all I needed to know. Now we turn to it whenever we need to feed our hungry bunch or want some comfy leftovers for the days ahead.

Ingredients

  • Ground beef: Makes up the filling base. Pick 80/20 for better taste or something leaner if you want
  • Bell pepper and onions: Give important flavors and a bit of sweetness when they cook down
  • Taco seasoning: Adds Mexican taste throughout. Ready-made works fine but making your own lets you adjust salt and heat
  • Bisquick: Makes the perfect slightly sweet bottom layer that works well with the savory stuff on top
  • Sour cream and mayonnaise: Mix together for the rich topping that makes this bake stand out
  • Cheddar cheese: Gives that can't-resist melty goodness. Go with sharp for more punch
  • Green chilies: Add mild warmth and true southwestern flavor without too much spice
  • Canned tomatoes and corn: Add brightness, different textures and colors to balance the rich meat

How To Make Cattle Drive Casserole

Prepare the base:
Stir Bisquick with water until you get a loose batter feel. Spread it out in your greased dish, making sure it's even all around. The quick 5-minute cook just sets it enough to hold everything while letting it finish baking with everything else.
Create the meat mixture:
Cook the beef completely, breaking it up as you go. After draining, throwing in the veggies and spices lets them soak up all that meaty goodness while they soften. Don't skip the 10-minute simmer as it really brings out all the flavors and gets the veggies just right.
Layer the components:
Carefully put the meat mix over the partly baked base, trying not to tear it. Scatter tomatoes and corn evenly so every bite has some. Mix the creamy topping stuff really well before gently spreading it over everything.
Bake to perfection:
The half-hour in the oven lets everything come together while the cheese turns golden on top. Don't rush into cutting it after baking as letting it sit is really important for it to set up and serve easier.
A white bowl with a casserole in it. Pin it
A white bowl with a casserole in it. | chefmelt.com

Green chilies are my hidden trick in this dish. My grandma always said good southwestern cooking needs that gentle heat to cut through the richness. When my kids were little, they'd pick them out at first, but now they ask for extra chilies on their plates. It shows me that sometimes the best tastes take a while to grow on you.

Make Ahead Options

This bake works great as a do-ahead meal. You can fix it all up to the baking part, wrap it tight with foil, and keep it in the fridge for about a day. When you're ready to cook, just take it out roughly 30 minutes before to warm up a bit, then bake like normal, maybe adding 5-10 extra minutes. The tastes actually get better when everything sits together overnight.

Customization Ideas

The main recipe gives you a great starting point to make it your own. Try putting a layer of refried beans between the meat and biscuit bottom for more richness. You can swap half the beef for black beans to get more fiber. If you like it hot, throw in some diced jalapeños or a splash of hot sauce to the meat mix. Some folks enjoy adding guacamole or fresh avocado slices after it's baked to cool things down a bit.

A bowl of food with a dollop of sour cream on top. Pin it
A bowl of food with a dollop of sour cream on top. | chefmelt.com

Serving Suggestions

This filling dish works great by itself, but adding some sides makes the meal even better. A basic green salad with cilantro lime dressing gives a fresh contrast to the heavy bake. For a true southwestern feel, serve with Mexican rice or some seasoned black beans on the side. You can put out regular taco toppings like shredded lettuce, chopped tomatoes, sliced olives, and extra sour cream so everyone can fix their plate how they want. For casual get-togethers, corn chips or warm tortillas add a nice crunchy touch.

Frequently Asked Questions

→ Can I swap ground beef with another meat?

Sure thing! You can use ground turkey, chicken, or even plant-based substitutes for a twist or dietary needs.

→ Is it possible to make this dish ahead?

Definitely! Prepare everything up to the baking step, keep it in the fridge for up to a day, and bake when you're ready.

→ What's the best way to store the leftovers?

Keep leftovers in a sealed container in the fridge for up to three days. Reheat in the microwave or oven until hot.

→ Can I throw in extra veggies?

Of course! Add diced zucchini, mushrooms, or spinach for a nutritious boost and added flavor.

→ What should I serve alongside this dish?

This goes great with a simple salad, some garlic bread, or steamed veggies to round out the meal.

→ Can I use a homemade biscuit mix instead of store-bought?

Yes! Feel free to use a homemade mix. Just make sure the dough’s a bit loose so everything bakes well.

Cattle Drive Dish

Layers of seasoned beef, creamy topping, and veggies. A warm, comforting choice for dinner.

Prep Time
15 Minutes
Cook Time
45 Minutes
Total Time
60 Minutes

Category: Main Dish Recipes

Difficulty: Intermediate

Cuisine: American

Yield: 8 Servings

Dietary: ~

Ingredients

→ Main Ingredients

01 14 ounces canned whole kernel corn, drained
02 14 ounces canned diced tomatoes, drained
03 2 packets taco seasoning or 6 tablespoons homemade taco blend
04 8 ounces shredded cheddar cheese, divided
05 1 medium green bell pepper, diced
06 2 pounds ground beef
07 1/4 teaspoon black pepper
08 4 ounces canned diced green chilies
09 1/2 cup sour cream
10 1/2 cup mayonnaise
11 2 cups Bisquick
12 2 small yellow onions, diced
13 1 1/4 cups water, divided

Instructions

Step 01

Set your oven to 350°F and let it warm up. Coat a 9x13-inch casserole dish with non-stick spray and leave it aside.

Step 02

Break apart the ground beef in a big skillet and cook it over medium-high heat until it browns completely. Drain any grease. Toss in the diced bell peppers, onions, taco seasoning, and about 1/2 cup of water. Mix well and simmer for 10 minutes until the veggies soften up. Turn off the heat and let it sit.

Step 03

Mix Bisquick with 3/4 cup water in a medium bowl until it turns into a loose dough. Spread the dough evenly across the bottom of your casserole dish. Bake for 5 minutes, then pull it out and leave your oven on at 350°F.

Step 04

Evenly spread the cooked beef mixture over the baked biscuit base. Sprinkle the drained tomatoes and corn across the top, making sure it’s all evenly layered.

Step 05

In a medium bowl, combine the sour cream, mayonnaise, half the shredded cheddar, green chilies, and black pepper. Spread this creamy mix evenly over the beef layer. Sprinkle the rest of the cheddar cheese on top of it.

Step 06

Pop the dish into the oven for 30 minutes. Once baked, let it rest for around 7-10 minutes to firm up a bit before you dig in. Add a sprinkle of fresh parsley to make it look extra nice, if you’d like.

Notes

  1. Let the dish rest for 7-10 minutes before you serve it.

Tools You'll Need

  • Big skillet
  • Medium-sized mixing bowl
  • 9x13-inch casserole dish
  • Non-stick cooking spray

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Includes dairy (cheddar, sour cream, mayo)
  • Contains gluten (from Bisquick)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 410
  • Total Fat: 25 g
  • Total Carbohydrate: 27 g
  • Protein: 20 g